Yes. Since you already have Dynamics 365 Customer Insights – Journeys (CI-J) integrated with Twilio, this is a good use case for the native SMS keyword capability.
Your target design should be:
Twilio inbound SMS → CI-J keyword recognition → phone/contact identification → consent/opt-in → confirmation SMS → customer becomes eligible for future SMS journeys.
The most important part is not the keyword itself; it is correctly implementing identity matching + consent + STOP handling + compliance around that keyword.
refer :
https://learn.microsoft.com/en-us/dynamics365/customer-insights/journeys/real-time-marketing-text-messaging
https://learn.microsoft.com/en-us/dynamics365/customer-insights/journeys/conversational-journeys-prerequisites
https://learn.microsoft.com/en-us/dynamics365/customer-insights/journeys/set-up-automated-sms-keyword-flow
