Integration Manager – The RPC Server Is Unavailable

During a recent implementation I was importing a file of 30,000 items into Microsoft Dynamics GP using Integration Manager when, part way through the integration, the following error started being produced:

9057:  ITEM-NUMBER-1 Insert Failed 6. Seconds 
    DOC 9057 ERROR: The RPC server is unavailable. (Exception from HRESULT: 0x800706BA) - The RPC server is unavailable. (Exception from HRESULT: 0x800706BA)
9058:  ITEM-NUMBER-2 Insert Failed 0. Seconds 
    DOC 9058 ERROR: The RPC server is unavailable. (Exception from HRESULT: 0x800706BA) - The RPC server is unavailable. (Exception from HRESULT: 0x800706BA)
9059:  ITEM-NUMBER-3 Insert Failed 0. Seconds 
    DOC 9059 ERROR: The RPC server is unavailable. (Exception from HRESULT: 0x800706BA) - The RPC server is unavailable. (Exception from HRESULT: 0x800706BA)

When I tried to restart the integration, I was presented with a popup box:

Integration Manager

The destination could not be initialized due to the following problem:
– The RPC server is unavailable. (Exception from HRESULT: 0x800706BA)
The RPC server is unavailable. (Exception from HRESULT: 0x800706BA)

I restarted Integration Manager, but the problem persisted until I eventually restarted Microsoft Dynamics GP itself. AFter doing this the integration could be started and run to completion with no further errors.