Hi Raed,
For ISV solutions, you can hide your modules for organizations that don't have a license key. For each license component, you can create a license code.
If you have a solution and an additional analytics license for that solution, you can think of creating two license codes.
The configuration keys can be used to turn on or off specific features or modules. You can link a license code to a configuration key. In that case, the configuration can't be enabled without a valid license code. You can build a hiearchy using the ParentKey property. If your solution has several modules, you can think of a main configuration key and some related key to manage specific features to be enabled or disabled.
Each object, such as a menu item, table, field, view, or form object can be linked with a configuration key. During runtime, it wil check if the key is enabled, otherwise it will not show the details on the user interface.
My recommendation is to not link a configuration key on tables and views in case you extend standard views. They might cause runtime errors if the license code or configuration key is not enabled.
In case you have batch jobs or code extensions, ensure you perform an additional check if your configuration key is enabled. I have seen an ISV table being continuous filled, even without a license or having the feature enabled.
The configuration key groups is used for one use case in the application. It is possible to have a "Commerce essentials" mode. When enabling this configuration key, it will disable all configuration keys, except those listed in the group. For normal use cases, you don't need a configuration key group.