Hi Thomas,
I would suggest you to try the workaround to get rid of the issue.
Note: Before trying the mitigation request you to take a full backup of the database and perform the steps
use MSCRM_CONFIG
Delete from OrganizationProperties where Id = '<ORG ID>' and ColumnName IN('SymmetricKeyPassword' , 'SymmetricKeySource')
--Remove key from DB
use ORG_MSCRM
drop symmetric key CrmSymmetricKey1
--Reset all values to null in CRM DB
Update EmailServerProfileBase set IncomingPassword = null, OutgoingPassword = null
Update MailBoxBase set Password = null
Update queuebase set emailpassword = null
Update usersettingsbase set emailpassword = null
update LocalConfigStoreBase set Value=null where Value is not null
update ServiceEndpointBase set SASKey=null where SASKey is not null
update ServiceEndpointBase set SASToken=null where SASToken is not null